Keith L. March, MD, PhD, FACC, has dedicated his career to bringing new medical approaches to patients. His publications include more than 150 manuscripts. He was the editor of the first book dedicated to cardiovascular gene transfer. Dr. March’s research has resulted in more than 55 worldwide patents, with others pending. He invented the Closer, a widely-utilized patented suture-mediated closure device which allows a patient to “walk off the table” after a catheterization without requiring prolonged bedrest. The Closer approach has been used worldwide to treat more than 8,000,000 patients.
His laboratory focuses on blood vessel biology, with a particular emphasis on the stem cells found in the adipose (fat) tissue, which his laboratory identified as cells with critical roles in blood vessel growth and control of inflammation, importantly mediated by their paracrine factors. From 2008-2012, he was Chair of the National Institutes of Health Data and Safety Monitoring Board overseeing cell therapy studies in the areas of heart, lung, and blood diseases. He has participated in numerous cell therapy trials, including those of the NIH Cardiovascular Cell Therapy Research Network (CCTRN).
In Fall 2017, Dr. March was recruited to the University of Florida to spearhead the University of Florida Center for Regenerative Medicine. Since then, he has worked to identify and develop clinical trials that will address key unmet medical needs using cell-based therapies at UF.
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